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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK9
All Species:
31.52
Human Site:
S180
Identified Species:
46.22
UniProt:
P50750
Number Species:
15
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50750
NP_001252.1
372
42778
S180
A
F
S
L
A
K
N
S
Q
P
N
R
Y
T
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094502
352
40482
S160
A
F
S
L
A
K
N
S
Q
P
N
R
Y
T
N
Dog
Lupus familis
XP_548446
534
59045
S342
A
F
S
L
A
K
N
S
Q
P
N
R
Y
T
N
Cat
Felis silvestris
Mouse
Mus musculus
NP_570930
372
42743
S180
A
F
S
L
A
K
N
S
Q
P
N
R
Y
T
N
Rat
Rattus norvegicus
Q641Z4
372
42743
S180
A
F
S
L
A
K
N
S
Q
P
N
R
Y
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520593
314
36161
W135
T
N
R
V
V
T
L
W
Y
R
P
P
E
L
L
Chicken
Gallus gallus
Q5ZKN1
372
42784
S180
A
F
S
L
A
K
N
S
Q
P
N
R
Y
T
N
Frog
Xenopus laevis
Q4V862
376
43205
S184
A
F
S
L
A
K
N
S
Q
P
N
K
Y
T
N
Zebra Danio
Brachydanio rerio
NP_997756
393
45129
S201
A
F
S
L
A
K
N
S
Q
G
N
R
Y
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477226
404
46768
E212
A
F
S
I
P
K
N
E
S
K
N
R
Y
T
N
Honey Bee
Apis mellifera
XP_396015
382
43973
G186
A
F
S
V
N
K
N
G
Q
P
N
R
Y
T
N
Nematode Worm
Caenorhab. elegans
Q9TVL3
478
53575
G250
V
Q
R
E
N
G
A
G
P
R
P
L
Y
T
N
Sea Urchin
Strong. purpuratus
XP_798269
410
46418
D209
A
F
S
L
P
K
G
D
A
P
N
R
Y
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFT8
505
56711
D192
L
A
R
S
Y
S
H
D
H
T
G
N
L
T
N
Baker's Yeast
Sacchar. cerevisiae
P23293
657
74221
G234
L
K
Y
P
G
G
A
G
S
G
A
K
Y
T
S
Red Bread Mold
Neurospora crassa
Q871M9
545
61347
E195
Q
P
G
K
G
S
G
E
G
K
R
D
Y
T
S
Conservation
Percent
Protein Identity:
100
N.A.
92.4
68.5
N.A.
98.6
98.6
N.A.
77.9
93
89.3
85.5
N.A.
66
72.7
43.3
67.3
Protein Similarity:
100
N.A.
93.5
69.4
N.A.
99.7
99.7
N.A.
80.3
95.4
94.1
89.5
N.A.
75.9
83.2
56.4
75.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
100
93.3
93.3
N.A.
66.6
80
20
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
100
100
93.3
N.A.
73.3
86.6
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36
25.2
31.7
Protein Similarity:
N.A.
N.A.
N.A.
51
39.4
45.6
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
69
7
0
0
50
0
13
0
7
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
13
0
0
0
7
0
0
0
% D
% Glu:
0
0
0
7
0
0
0
13
0
0
0
0
7
0
0
% E
% Phe:
0
69
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
13
13
13
19
7
13
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
7
0
7
0
69
0
0
0
13
0
13
0
0
0
% K
% Leu:
13
0
0
57
0
0
7
0
0
0
0
7
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
13
0
63
0
0
0
69
7
0
0
82
% N
% Pro:
0
7
0
7
13
0
0
0
7
57
13
7
0
0
0
% P
% Gln:
7
7
0
0
0
0
0
0
57
0
0
0
0
0
0
% Q
% Arg:
0
0
19
0
0
0
0
0
0
13
7
63
0
0
0
% R
% Ser:
0
0
69
7
0
13
0
50
13
0
0
0
0
0
13
% S
% Thr:
7
0
0
0
0
7
0
0
0
7
0
0
0
94
0
% T
% Val:
7
0
0
13
7
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
0
0
7
0
0
0
88
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _